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Proline

proline

(Science: amino acid) One of the 20 amino acids directly coded for in proteins. Structure differs from all the others, in that its side chain is bonded to the nitrogen of the _ amino group, as well as the _ carbon. This makes the amino group a secondary amine and so proline is described as an imino acid. Has strong influence on secondary structure of proteins and is much more abundant in collagens than in other proteins, occurring especially in the sequence glycine proline hydroxyproline. A proline rich region seems to characterise the binding site of SH3 domains. An amino acid that is found in many proteins (especially collagen).One of 20 amino acids commonly found as part of a protein.


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Location of mutation in E. Coli biosynthetic auxotroph

I have isolated a mutant, streaked it onto pool plates and determined that it grows on minimal medium with the following additions: proline, arginine, ornithine, aspartic acid, proline, glutamic acid, inositol. Since the mutant was mutagenized according to 99.9% killing etc. it should only ...

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by Jeaneai
Mon Nov 26, 2012 4:56 pm
 
Forum: Genetics
Topic: Location of mutation in E. Coli biosynthetic auxotroph
Replies: 0
Views: 996

What food have a lot of l-proline, an amino acid?

Hello friends, It is a non-essential protein, but I want to know from what type of food we can have a lot of it. Best Regards Cindy Hang

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by CindyHang
Mon Oct 29, 2012 11:44 am
 
Forum: Molecular Biology
Topic: What food have a lot of l-proline, an amino acid?
Replies: 2
Views: 1501

Re: how to memorize the amino acid

... you a hint, which our prof gave us. Look on the amino acids as on derivatives of alanine, instead of glycine. Glycine is of course an exception. Proline as well, since it is an imino acid. Alanine is the "basic" amino acid. Now, serine and cysteine are hydroxy- and thiol derivatives. ...

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by JackBean
Thu Feb 09, 2012 9:52 am
 
Forum: General Discussion
Topic: how to memorize the amino acid
Replies: 4
Views: 5284

medium choice confusion

... - Arg- cannot synthesise arginine thr - Thr- cannot synthesise threonine phe - Phe- cannot synthesise phenylalanine pro- Pro- cannot synthesise proline str r Str r resistant to streptomycin azi r Azi r resistant to sodium azide a)What is the simplest defined medium you can use to grow the F- ...

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by ashhh
Sun Aug 21, 2011 2:58 pm
 
Forum: Molecular Biology
Topic: medium choice confusion
Replies: 1
Views: 3134

Do we know all the proteins (and their primary structure!)?

... every protein sequence. The genes do not code to the post traductionnal modifications. As exemple, on the collagen sequence, we have a repeat of proline but in the real molecule, some aa are hydroxyproline. In addition, some protein need to loose a peptide to be active or to modify their activity. ...

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by stephroche
Fri Apr 29, 2011 1:57 pm
 
Forum: Cell Biology
Topic: Do we know all the proteins (and their primary structure!)?
Replies: 5
Views: 3128
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