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Progabide

progabide

(4-[(4-chlorophenyl, 5-fluoro-2-hydroxyphenyl) methylene]amino-butabeamide;an anticonvulsant which is a lipid-soluble derivative of the amidated form of gamma-aminobutyric acid (GABAmide) that, unlike gamma-aminobutyric acid (gABA) itself, is able to cross the blood-brain barrier. Once inside the brain the drug is converted to several metabolites, some of which are active forms of GABA or related compounds which act on gABA receptors to increase inhibition in the brain.


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