(Science: chemical) The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Pharmacological action: renal agents, uricosuric agents.
Chemical name: benzoic acid, 4-((dipropylamino)sulfonyl)-
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... Ever year around 300 people die from these reactions. Some brand names that you should avoid include: methotrexate (Rheumatrex, Trexall), probenecid (Benemid), a sulfa drug (such as Bactrim or Septra), an antibiotic such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin ...
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