Dictionary » P » Presynaptic




(1) Of, or relating to the transmitting end of a discharge across a synapse.

(2) Pertaining to or being situated at the proximal side of a synapse.


The term is used in physiology to refer to the transmitting or proximal side of a synapse, such as a presynaptic cell (e.g. a neuron) which releases neurotransmitters that bind with the receptors of a postsynaptic cell (e.g. a muscle cell, a gland cell or a neuron).

Word origin: pre- (before) + synaptic ยป synapse

Compare: postsynaptic
See also: synapse

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Re: human physiology qu please help

The example listed above is a great one. Just to fill in SOME of the details: When there is an action potential in a presynaptic neuron, it results in Neurotransmitter release from the axon terminals. The neurotransmitter (for example Acetylcholine) binds to receptors of the postsynaptic ...

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by LeslieSamuel
Thu Dec 24, 2009 2:38 am
Forum: Physiology
Topic: human physiology qu please help
Replies: 3
Views: 5758

human physiology qu please help

can anyone help me answer this qu : explain how an action potential in a presynaptic nerve cell may initiate graded potentials in dentrites of post-synaptic nerve cells

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by grainne89
Tue Dec 15, 2009 11:44 am
Forum: Physiology
Topic: human physiology qu please help
Replies: 3
Views: 5758

PostSynaptic Neuron

As you know, postsynaptic neuron is excited by the neurotransmitter released by the presynaptic neuron at synaptic cleft. The effect of this neurotransmitter is terminated by different ways. 1. It may be degraded by the enzyme (as you mentioned), thus preventing continous ...

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by freshbiology
Fri Jul 24, 2009 4:40 pm
Forum: General Discussion
Topic: PostSynaptic Neuron
Replies: 3
Views: 11333

Calcium ions

... - for instance how does the influx of calcium ions into a nerve ending bring about vesicles containing neurotransmitter moving towards the presynaptic membrane? Thanks in advance

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by ferrari599
Thu Nov 20, 2008 6:17 pm
Forum: Human Biology
Topic: Calcium ions
Replies: 2
Views: 4352


... enter how do they bring about the release of neurotransmitter, from what I have heard the vesicles containing the neurotransmitter bind to the presynaptic membrane and release their contents but I dont understand the mechanism behind this, I mean how does the entry of Ca ions bring this about

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by Ilyaas
Sun Dec 04, 2005 11:44 am
Forum: Molecular Biology
Topic: Synapse
Replies: 7
Views: 5089
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