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prekallikrein

(Science: chemical) A plasma protein which is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. The absence of prekallikrein in plasma leads to fletcher factor deficiency, a congenital disease.

Chemical name: Kallikreinogen