Edith Potter is an American pathologist that established perinatal pathology. One of her contributions is the understanding of Rh disease, i.e. one of the causes of hemolytic disease of the newborn. She was also the one that established the link between the atypical physical appearance and renal agenesis. The latter is referred to as Potter syndrome. In Potter syndrome, the fetus developed clubbed feet and hypoplastic lung. It was found to be associated with oligohydramnios. Oligohydramnios refers to the deficiency of amniotic fluid in utero. The amniotic fluid is essential for the growth of the fetus within the mother's womb. It expands the amniotic sac that surrounds the fetus, providing an adequate space for fetus to move and grow. It also prevents physical injury to the growing fetus as the latter is kept afloat inside the fluid-filled amniotic sac. Too little amniotic fluid would therefore affect the growth of the fetus. Apparently, it may also lead to the development of a hypoplastic lung. A hypoplastic lung is an underdeveloped lung and life-threatening. The underdeveloped lung due to oligohyramnios may lead to inefficient lung function, particularly oxygenation, and to perinatal death.1
1 Oligohydramnios. Biology-Online.org Dictionary. Retrieved from [].