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Polygenic disease



An inherited disease determined by the effects of the simultaneous interaction of several genes


Because of the complexity of genetic interactions, a polygenic disease does not follow a pattern the same way a monogenic disease does.


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Reduced penetrance vs. multifactorial?

Can anybody explain to me how you would be able to distinguish between a disease caused by a single-gene trait with low penetrance and a multifactorial ... something as a single gene disorder with reduced penetrance and a polygenic disorder? (i.e. is it still meaningful to describe a disease as ...

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by Grumbot
Mon Apr 04, 2011 4:23 pm
Forum: Genetics
Topic: Reduced penetrance vs. multifactorial?
Replies: 1
Views: 3042

Kegg pathway analysis of genes involved in polygenic disease

... contains KEGG pathway analyses of several hundred genes inplicated in Alzheimer's disease, Bipolar disorder, schizophrenia and Parkinson's disease

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by chriscar
Sat Mar 12, 2011 9:44 am
Forum: Human Biology
Topic: Kegg pathway analysis of genes involved in polygenic disease
Replies: 0
Views: 838

Biology HW help

... a mutation has occurred. Save Answer 11. Week 7 Q.11 (Points: 5) When a disease is said to have a multifactorial basis, it means that 1. it tends ... 19. Week 7 Q.19 (Points: 5) Which of the following is an example of polygenic inheritance ? 1. Huntington's disease in humans 2. skin pigmentation ...

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by sharingan23
Fri Feb 26, 2010 9:09 am
Forum: Genetics
Topic: Biology HW help
Replies: 1
Views: 15122

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