Poly a tail

Definition

noun

A long stretch of (about ten to 200 or more) adenine nucleotides added to the "tail" or 3' end of the pre-mRNA via the process called polyadenylation catalyzed by the enzyme, polyadenylate polymerase (PAP).


Supplement

In eukaryotic organisms, most messenger RNA molecules end with a poly-A stretch at their 3' ends. It is believed to protect the mRNA from degradation by exonucleases, and is essential for transcription termination, for export of the mRNA from the nucleus, and for translation.


See also: adenine, mRNA, polyadenylation.


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified on 15 August 2008, at 10:39. This page has been accessed 36,116 times. 
What links here | Related changes | Permanent link