Dictionary » P » Point mutation

Point mutation

Definition

noun, plural: point mutations

A mutation in DNA or RNA molecule involving a change of only one nucleotide base.


Supplement

This type of mutation occurring in noncoding sequences often does not result in an altered amino acid sequence during translation. If a mutation in the promoter sequence of a gene occurs, the effect may be apparent since the expression of the gene may cause changes in the amino acid sequence, as well as the structure and function of the protein product.

Point mutations may be classified based on functionality:

Depending on the type of nitrogenous base involved, this type of mutation may be categorized as:

  • transition
  • transversion

Sometimes, point mutation also covers mutations caused by single nucleotide insertions or deletions (which are types of frameshift mutation).


Synonym:


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Re:

Theory 2) At one point, humans will probably stop growing body hair because of an evolutionary mechanism that will influence mutation and cause our offspring to not have hair follicles, because they are not necessary or helpful ...

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by Cat
Fri Oct 31, 2014 2:02 am
 
Forum: Evolution
Topic: Can human body hair disappear as a result of... clothing?
Replies: 4
Views: 1370

Can human body hair disappear as a result of... clothing?

... when you already have hair doesn't kill anybody. Theory 2) At one point, humans will probably stop growing body hair because of an evolutionary mechanism that will influence mutation and cause our offspring to not have hair follicles, because they are not necessary ...

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by jplr
Sat Oct 11, 2014 6:16 pm
 
Forum: Evolution
Topic: Can human body hair disappear as a result of... clothing?
Replies: 4
Views: 1370

Hyperadrenergic POTS

... in a kindred with hyperadrenergic POTS. These individuals have a single point mutation in the norepinephrine transporter (NET). The resultant inability to adequately clear ...

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by rmorrison
Wed Mar 19, 2014 5:38 pm
 
Forum: Human Biology
Topic: Hyperadrenergic POTS
Replies: 0
Views: 6040

Polymorphism and Mutation

Just about numbers. A mutation is a change to a single individual that may or may not be propagated. For example a single point mutation where a base is replaced or deleted from a strand of DNA. This may cause the individual some ...

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by Babybel56
Wed Mar 05, 2014 3:39 am
 
Forum: Molecular Biology
Topic: Polymorphism and Mutation
Replies: 2
Views: 2957

What makes dominant allele dominant?

... transcription to protein post-translational modifications. There can be mutation in the promotor changing significantly expression. If the binding ... will be impaired, there will be much less of protein made. Single point mutations can lead to differences in binding of miRNAs. On the protein ...

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by JackBean
Thu Feb 27, 2014 5:20 pm
 
Forum: Genetics
Topic: What makes dominant allele dominant?
Replies: 7
Views: 7699
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