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Dictionary » P » Pluripotency PluripotencyDefinition noun The ability of a biological compound to produce several distinct biological responses in many organs or tissues. (developmental biology) The ability of the cell to develop into more than one cell type.
In immunology, pluripotency is shown by some cytokines such as interferon γ that activates some cell types and inhibits other cell types. For instance, interferon gamma stimulates antibody class switching in B cells, promotes maturation of NK cells, and activates intracellular killing in macrophages. In developmental biology, pluripotency is exhibited when a stem cell gives rise to many adult cell types.
Compare: unipotency, totipotentcy, multipotency.
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Results from our forumRecent discovery in stem cell research.... an embryonic stem cell shows 6k genes with 5 fold differences. Comparing iPS and hES, 1267 genes showed 5 fold differences. 3. To test pluripotency, they injected the cells in to irradiated mice. Tumors formed consisting of various tissues-gut, cartilage, neural, muscle. 4. 20% of mice ...
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human foreskin stem cellsThe transcription factor Oct 4 is required for the maintenance of stem cell pluripotency and self-renewal, and activity of Oct 4 is essential for the identity of the pluripotent founder cell population in the mammalian. Recently we found that the cells from adult ...
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