Dictionary » P » Pleiotropic



Having multiple effects. For example: the cyclic AMP concentration in a cell will have a variety of effects because the cAMP acts to control a protein kinase that in turn affects a variety of proteins.

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Re: Theories - Origin of Life

... regulated process So what is PhoP/PhoQ regulation? Here is a good description of this regulation http://jb.asm.org/content/183/6/1835.full The Pleiotropic Two-Component Regulatory System PhoP-PhoQ Here, I first discuss how the PhoP-PhoQ two-component system responds to environmental cues and ...

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by scottie
Tue Jan 17, 2012 11:04 pm
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 563
Views: 1127873

Evolution - Natural Selection FLAWED?

... So for that reason, as Grassé puts it, "No matter how numerous they may be, mutations do not produce any kind of evolution."25 The Pleiotropic Effect The most important proof that mutations lead only to damage, is the process of genetic coding. Almost all of the genes in a fully ...

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by Thermopylae
Sun Feb 18, 2007 3:52 pm
Forum: Evolution
Topic: Evolution - Natural Selection FLAWED?
Replies: 9
Views: 25147

Pleiotropic loci on different chromosomes?

Hi, I have an issue on which clarification would be much appreciated: Can pleiotropic loci be located on different chromosomes? Intuitively I think yes, but if anyone could confirm it to me, that would be great. Cheers J

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by j.m
Sun Feb 11, 2007 1:35 pm
Forum: Genetics
Topic: Pleiotropic loci on different chromosomes?
Replies: 1
Views: 1230

The Fiber Disease

... secreted by a wide variety of cells in response to diverse stimuli, and mediate autocrine, paracrine, or endocrine effects that are often pleiotropic and redundant. Their molecular weight lies between 6 and 70 kd. The cytokines of immunologic relevance are primarily those that are formed ...

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by Skytroll
Sun Sep 10, 2006 7:16 pm
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6244808

New Virus And The Origins Of Life

... This gene switches on other genes during embryonic growth and is responsible for normal development of body regions. The mutated gene results in pleiotropic effects; it alters a number of features in the head, not only causing blindness, but also affecting teeth and taste buds. Fish with the ...

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by David George
Fri Mar 10, 2006 6:40 am
Forum: Evolution
Topic: New Virus And The Origins Of Life
Replies: 28
Views: 12027
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