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Plasmid

Definition

noun, plural: plasmids

A linear or circular double-stranded DNA that is capable of replicating independently of the chromosomal DNA.


Supplement

Certain plasmids are able to insert themselves into the chromosomes particularly in regions where there is a common sequence of nucleotides. Hence, they are used in recombinant DNA technology and research as means for transferring genes between cells or as cloning vectors.

Plasmids are important in certain bacteria since plasmids code for proteins, especially enzymes, which can confer resistance to antibiotics. Plasmids are ubiquitous in prokaryotes but they have also been found in a number of eukaryotes, e.g. Saccharomyces cerevisiae, which may contain a 2-micrometre-ring of plasmid.


Word origin: The term plasmid was first introduced by the American molecular biologist Joshua Lederberg in 1952.
Synonym: extrachromosomal element.
See also: DNA, chromosome.



User Contributions:

  • Plasmid (PLAZ mid) - a genetic structure that can replicate independently of the main chromosome(s) of a cell; usually, a circular DNA molecule in bacteria ( prokaryotes).

Please contribute to this project, if you have more information about this term feel free to edit this page



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pGP704

Here you have author and some publications http://plasmid.med.harvard.edu/PLASMID/GetVectorDetail.do?vectorid=249

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by JackBean
Tue Aug 19, 2014 5:37 pm
 
Forum: Molecular Biology
Topic: pGP704
Replies: 2
Views: 258

Re: pGP704

... in the methods and then the paper should provide their source. Call the source and ask. I imagine the Harvard or Yale microbial library has the plasmid you are looking for.

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by daniel.kurz
Wed Aug 13, 2014 4:53 am
 
Forum: Molecular Biology
Topic: pGP704
Replies: 2
Views: 258

pGP704

Can any one suggest how do i get plasmid pGP704 ?

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by Helics
Mon Aug 11, 2014 9:46 am
 
Forum: Molecular Biology
Topic: pGP704
Replies: 2
Views: 258

Re: Plasmid yield/concentration

Dear, scientist please give a response.

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by Helics
Sat Aug 02, 2014 3:55 am
 
Forum: Molecular Biology
Topic: Plasmid yield/concentration
Replies: 1
Views: 405

Plasmid yield/concentration

What is the difference between high yield plasmid and high concentration plasmid ?

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by Helics
Thu Jul 31, 2014 3:40 pm
 
Forum: Molecular Biology
Topic: Plasmid yield/concentration
Replies: 1
Views: 405
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