Plaque-forming unit

Definition

A measure of the quantity of individual infectious particles (e.g. virus particles) based on the number of plaque formed per unit volume.


Supplement

Theoretically, the plaque-forming unit includes only the infectious virus particles since a virus particle failing to infect a host cell will not be able to produce a plaque, hence, will not be counted. PFU rules out possible multiple-hit phenomena and include only the particles capable of infecting cells on their own. Thus, one PFU means one lytic event (or one infectious virus particle).


Abbreviation: PFU
Compare: colony-forming unit (CFU).


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified on 7 October 2008, at 08:11. This page has been accessed 26,964 times. 
What links here | Related changes | Permanent link