Dictionary » P » Phosphorylation

Phosphorylation

Definition

noun, plural: phosphorylations

The transferring of phosphoryl group from a donor to the recipient molecule


Supplement

Phosphorylation is important in living cells since it is through this that energy-rich molecules (e.g. ATPs) are formed. For instance, a phosphoryl group (phosphate) is added to ADP, thus forming ATP, usually catalysed by phosphorylases and kinases.


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Re: Why is ATP rather than GTP, CTP or TTP the energy currency?

... and there would be nothing to drive ATP hydrolysis forwards) - it is kept far from equilibrium by the continual synthesis of ATP through oxidative phosphorylation. Is the ratio of GTP:GDP and therefore the energy released through hydrolysis similar?

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by Maus
Tue Feb 03, 2015 6:46 pm
 
Forum: Molecular Biology
Topic: Why is ATP rather than GTP, CTP or TTP the energy currency?
Replies: 6
Views: 9517

Re: Types of phosphorylation ?

Substrate level phosphorylation takes place inside the mitochondria during glycolosis and the Krebs cycle. Oxidative phosphorylation takes place in the membranes of the mitochondria during the electron transport chain. Photo phosphorylation ...

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by cash
Sun Nov 03, 2013 3:55 am
 
Forum: Cell Biology
Topic: Types of phosphorylation ?
Replies: 5
Views: 11533

Protein synthesis during S phase

... is active during replication. I was guessing the inactivation of all other protein synthesis had something to do with CDK/cyclin levels, some phosphorylation, or something to do with steric impedement at the origin of replication. Still, that doesn't explain the histone part...

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by yuriw
Wed Sep 25, 2013 4:14 pm
 
Forum: Cell Biology
Topic: Protein synthesis during S phase
Replies: 3
Views: 2785

Fail to see under physiological stimulation

activate Src in sense of expression or phosphorylation? Can you check the Src is expressed in the first place?

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by JackBean
Tue Aug 27, 2013 9:36 am
 
Forum: Cell Biology
Topic: Fail to see under physiological stimulation
Replies: 6
Views: 2717

Fail to see under physiological stimulation

... of growth factor that is known to activate endogenous Src. I had tried looking at both GFP-tagged exogenous or endogenous but all fail to see the phosphorylation of my protein evoked by PDGF.

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by kingsupercat
Mon Aug 26, 2013 2:37 am
 
Forum: Cell Biology
Topic: Fail to see under physiological stimulation
Replies: 6
Views: 2717
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