phosphoinositide --> phosphatidylinositol
signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: iP3). Both the diacyl glycerol and products act as second messengers.
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... messengers are not soluble in water. Use the back button to return to the main document. Glossary IRS-1 = insulin receptor substrate 1 PDK1 = 3-phosphoinositide dependent kinase 1 PI-3K = phosphatidylinositol 3 kinase PIP2 = phosphatidylinositol 4,5 bisphosphate PIP3 = phosphatidylinositol 3,4,5 ...
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