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Phosphodiester bond

phosphodiester bond

(Science: chemistry) Not a precise term. Refers to any molecule in which two parts are joined through a phosphate group.

Examples are found in rNA, dNA, phospholipids, cyclic nucleotides, nucleotide diphosphates and triphosphates.

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The question about TATA sequence flexibility

... are also two symmetrical asparagine amino acids that form hydrogen bonds at the very center. The combination of the unusual flexibility of TATA ... know where exactly it bends, does each bond bend itself? Or maybe the phosphodiester bonds are stretched and contracted when bending the DNA molecule ...

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by Fantomas
Sat Aug 31, 2013 10:57 am
Forum: Molecular Biology
Topic: The question about TATA sequence flexibility
Replies: 1
Views: 1781

What happens to free phosphates after DNA elongation in PCR?

... the nucleotide are removed (creating the energy necessary to form the phosphodiester bond that attaches the remaining phosphate group to the growing chain). What happens to those ...

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by Melstmu2010
Thu Jun 23, 2011 8:43 pm
Forum: General Discussion
Topic: What happens to free phosphates after DNA elongation in PCR?
Replies: 1
Views: 1550

Re: DNA backbone breakage

... made up of alternative sugar and phosphate are held together by Phosphodiester bond. Phosphodiester bond is a covalend bond, so energy is required to more for breaking phosphodiester ...

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by kanagasundar
Tue Oct 05, 2010 3:54 am
Forum: Genetics
Topic: DNA backbone breakage
Replies: 5
Views: 8508

Re: DNA Replication Lagging Strand

... to where the primer was) DNA Ligase DNAse breaks up DNA at the phosphodiester bond, and RNA polymerase makes RNA. I still don't know which one of these isn't used.

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by firecloak
Fri Sep 17, 2010 7:03 pm
Forum: Genetics
Topic: DNA Replication Lagging Strand
Replies: 6
Views: 5895

Re: Generation of DNA nucleotides

... into the template nucleotide. If the nucleotide triphosphate hydrogen bonds correctly with the template nucleotide, the new phosphodiester linkage forms. If the nucleotide triphosphate is the wrong one then usually ...

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by jonmoulton
Thu Jan 14, 2010 5:11 pm
Forum: Molecular Biology
Topic: Generation of DNA nucleotides
Replies: 65
Views: 59165
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