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Phosphate group


noun, plural: phosphate groups

(biochemistry) A functional group or radical comprised of phosphorus attached to four oxygen, and with a net negative charge, thus represented as PO4-


The phosphate group is important in living things in different ways. Firstly, it is an important structural component of nucleotide, which is the basic structural unit of DNA and RNA. Secondly, it is a component of energy-rich molecules, such as ATP. Thirdly, it is also bound to coenzymes like NADP / NADPH involved in anabolic reactions (such as photosynthesis in plants and lipid synthesis in animals). It is also a part of the hydrophilic head of phospholipids in biological membrane.

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Questions on the Sodium Potassium Pump and Enzymes

Although the Sodium Pump is an ATPase, during it's cycle there is a phosphate group being added and taken away from the protein so surely kinase and phosphotase are involved ...

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by JoWillyTso
Mon Nov 05, 2012 5:50 pm
Forum: Cell Biology
Topic: Questions on the Sodium Potassium Pump and Enzymes
Replies: 3
Views: 5035

Blood Banks - Storage Media.

... days at 1°- 6°C when treated with acid-citrate-dextrose (ACD), citrate-phosphate-dextrose (CPD) or citrate-phosphate-double dextrose (CP2D) and ... the blood donated are not being transfused to a receiver matching blood group, then the Blood donated by the Blood Donor will be no use ? Thanks ...

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by prashantakerkar
Wed Nov 09, 2011 10:42 am
Forum: Human Biology
Topic: Blood Banks - Storage Media.
Replies: 2
Views: 1531

How does phospholipids aid the cell and the rest of the body

... it has both hodrophobic (fatty acids) and hydrophilic (glycerol, phosphate and the rest), thus the molecule must be able to pass both parts ... there is the structure (the saturation) of the fatty acids and also the group attached to the phosphate, whichc differ on both sides of membrane.

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by JackBean
Thu Sep 15, 2011 5:31 am
Forum: Molecular Biology
Topic: How does phospholipids aid the cell and the rest of the body
Replies: 7
Views: 9080

What happens to free phosphates after DNA elongation in PCR?

... adds free nucleotides to the 3' OH end of template DNA, 2 of the 3 phosphates of the nucleotide are removed (creating the energy necessary to form the phosphodiester bond that attaches the remaining phosphate group to the growing chain). What happens to those 2 phosphates that are removed? ...

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by Melstmu2010
Thu Jun 23, 2011 8:43 pm
Forum: General Discussion
Topic: What happens to free phosphates after DNA elongation in PCR?
Replies: 1
Views: 1734

How ATP works

ATP can change the enzymatic conformation by adding a phosphate group to it. This changes the conformation because the phosphate group is polar and is negatively ...

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by Taylosr
Wed May 11, 2011 1:44 am
Forum: Molecular Biology
Topic: How ATP works
Replies: 5
Views: 6423
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