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Phagocytosis

Definition

noun

The process of engulfing and ingestion of particles by the cell or a phagocyte (e.g. macrophage) to form a phagosome (or food vacuole), which in turn fuse with lysosome and become phagolysosome where the engulfed material is eventually digested or degraded and either released extracellularly via exocytosis, or released intracellularly to undergo further processing.


Supplement

Phagocytosis is the mechanism used by many protists (e.g. amoeba) to acquire nutrients. In humans and other multicellular animals, phagocytosis is an important defense mechanism against infection by microorganisms (e.g. bacteria) and the process of removing cell debris (e.g. dead tissue cells) and other foreign bodies.

Steps of a macrophage ingesting a pathogen:
a. Ingestion through phagocytosis, a phagosome is formed
b. The fusion of lysosomes with the phagosome creates a phagolysosome; the pathogen is broken down by enzymes
c. Waste material is expelled or assimilated.


Word origin: phago: G, comb. form akin to phageǐn to eat, devour + cyte: G. kutos, hollow vessel + -osis: expressing state or condition.
Related forms: phagocyte (noun), phagocytic (adjective) – as in “a phagocytotic cell”, phagocytose (verb) -- as in “to phagocytose particles”.

Compare: pinocytosis.
See also: endocytosis, plasma membrane.


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Re: Help with indentifying object - can't narrow to even kingdom

... a large ameba with thousands of individual nuclei that feeds by engulfing its food (mostly bacteria) with pseudopodia in a process called phagocytosis. Thus the slime mold ingests its food and then digests it. When the plasmodium runs out of food, or environmental conditions become harsh, ...

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by Sadial
Fri Jul 26, 2013 6:29 pm
 
Forum: General Discussion
Topic: Help with indentifying object - can't narrow to even kingdom
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Views: 3509

Re: Are dendritic cells phagocytes?

Yes http://www.ask4biology.com/immunology/phagocytosis

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by mavis
Tue Feb 26, 2013 7:10 am
 
Forum: Cell Biology
Topic: Are dendritic cells phagocytes?
Replies: 4
Views: 5214

Re: Answer this question. Coming from my module drills.

Phagocyte has lysozyme where the phagocytosis occur.

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by mavis
Thu Feb 21, 2013 5:35 am
 
Forum: Cell Biology
Topic: Answer this question. Coming from my module drills.
Replies: 3
Views: 2533

Are dendritic cells phagocytes?

... sure what your textbook is, but the ones I checked quite explicitly labelled dendritic cells as "professional phagocytes" - meaning that phagocytosis is one of their primary duties. You could, for example, check Janeway's Immunobiology, which is a highly regarded and widely available ...

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by biohazard
Tue Nov 06, 2012 8:08 am
 
Forum: Cell Biology
Topic: Are dendritic cells phagocytes?
Replies: 4
Views: 5214

Re: Difference between T-Cell and Phagocyte?

... of the two facts, biology noivce, as my username, but it was already taken. Then I used the other, here by chance. I liked your clarification for phagocytosis and endocytosis - answered one of my long time questions. I have some further questions if you don't mind: 1. Does B cell process the endocyted ...

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by aptitude
Sun Sep 11, 2011 7:27 am
 
Forum: Physiology
Topic: Difference between T-Cell and Phagocyte?
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