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Peripheral membrane protein

Definition

noun, plural: peripheral membrane proteins

A protein that temporarily adheres to the biological membrane, either to the lipid bilayer or to integral proteins by a combination of hydrophobic, electrostatic, and other non-covalent interactions.


Supplement

Peripheral membrane proteins are located on the peripheral regions of the lipid biliayer of biological membranes. Examples of peripheral membrane proteins are proteins involved in electron transport chains, such as cytochrome c, cupredoxins, high potential iron protein, adrenodoxin reductase, some flavoproteins, and others.

Other peripheral membrane proteins are the carriers of non-polar compounds that facilitate transport of phosphatidylinositol, tocopherol, gangliosides, glycolipids, sterol derivatives, retinol, or fatty acids.


Word origin: peripheral < periphery: LL peripherīa < Gk periphéreia circumference, lit., a bearing round + -al.

Synonym: extrinsic protein.
Compare: integral membrane protein.
See also: cell membrane, fluid mosaic model.


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Protein movment in cell membrane?

I was reading about the phospholipid bilayer/membranes and how it's fluid like in nature which is the reason why molecules such ... including integral proteins which are firmly bound to the membrane and peripheral proteins which are not even embedded in the lipid bilayer. If integral ...

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Tue Dec 13, 2011 4:42 pm
 
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by chrisPbacon
Fri Sep 30, 2011 10:36 pm
 
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by UnivCalgary
Wed Jun 13, 2007 4:02 am
 
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Topic: Protein Concentration vs Membrane Fluidity
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Protein Concentration vs Membrane Fluidity

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by UnivCalgary
Wed Jun 13, 2007 4:01 am
 
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Tue Apr 17, 2007 2:25 am
 
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