The perinucluear space of most cells is 20-40nm wide. Since the endoplasmic reticulum is contiguous to nuclear membrane the endoplasmic reticulum lumen is therefore contiguous to perinuclear space as well.
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... to how histones help coil DNA) I'm thinking in the 2nd one that the space between the 2 circles may represent the perinuclear space surrounded by the outer and inner membranes of the nucleus. Any other ideas ...
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