Dictionary » P » Perforin



(Science: protein) Perforins 1 and 2 form tubular transmembrane complexes (16nm diameter) at the sites of target cell lysis by natural killer cells and cytotoxic T-cells.

Please contribute to this project, if you have more information about this term feel free to edit this page

Results from our forum

Immune System

... as well make a list out of this! - Cell death can be due to phagocytosis or by the release of membrane perforating enzymes such as granzyme and perforin - both of these from NK or cytotoxic T-cells - that cause apoptosis. - Complement directly leads to the destruction of cells by causing a membrane ...

See entire post
by Babybel56
Tue May 10, 2011 7:05 pm
Forum: Human Biology
Topic: Immune System
Replies: 4
Views: 6793

Help with Immunology

... Thelper cells then stimulate both Tcytotoxic and Naive Bcells. T cytotoxic cells move to the site of inflammation by chemotaxis and either secrete perforin or differentiate into T suppresor cells. Stimulated Bcells either differentiate into plasma cells or memory b cells. Plasma cells secrete antibodies, ...

See entire post
by FoxintheBox
Tue Dec 18, 2007 11:45 pm
Forum: Physiology
Topic: Help with Immunology
Replies: 3
Views: 6983

Crazy question on Bio entrance exam

hey, you inveted for example a new complement system and a new way in which cytotoxic T-cells release their granzymes in a cell without perforin. :idea:

See entire post
by sdekivit
Sun Sep 17, 2006 8:23 pm
Forum: General Discussion
Topic: Crazy question on Bio entrance exam
Replies: 5
Views: 2338

How does your body get rid of viruses

... CD3, a marker of all lymphocytes. They play a role in non-specific cytoxicity, destroying pathogen-infected cells by releasing hydrolitic enzymes, perforin and granzyme. In a standard blood smear preparation they appear just like lymphocytes. You can distinguish them from lymphocytes by applying ...

See entire post
by Dr.Stein
Sat Jul 16, 2005 1:22 pm
Forum: Human Biology
Topic: How does your body get rid of viruses
Replies: 24
Views: 50088

This page was last modified 21:16, 3 October 2005. This page has been accessed 5,649 times. 
What links here | Related changes | Permanent link