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Peptide

Definition

noun, plural: peptides

A compound consisting of amino acids connected by an amide bond


Supplement

Peptides care comprised of monomers of amino acids that are linked in chain via an amide bond. The bond is formed between the carboxyl group of one amino acid and the amine group of another. A peptide comprised of two amino acids is called dipeptide. A peptide that has three amino acids is called a tripeptide; if it has four, tetrapeptide, and so forth.

Peptides can be classified according to function. Examples of peptide groups based on their function include hormones, neuropeptides, and alkaloids. They can also be classified according to how they are produced. Ribosomal peptides are produced through mRNA translation whereas nonribosomal peptides (e.g. glutathione) are those produced by enzymes specific to each peptide rather than by a ribosome. Peptones are peptides that are not as common as the ribosomal and nonribosomal peptides. They are produced from the proteolysis of animal milk or meat.


Word origin: Ancient Greek peptós (digested)

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... no commercially available vaccine or efficacious therapeutic for any filovirus. In this study, PMO conjugated to arginine-rich cell-penetrating peptide (P-PMO) and nonconjugated PMO were assayed for the ability to inhibit EBOV infection in cell culture and in a mouse model of lethal EBOV infection. ...

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by jonmoulton
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by JackBean
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peptidyl transferase center?!

well, you can still take your peptide from that entries

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by JackBean
Mon Nov 11, 2013 2:18 pm
 
Forum: Bioinformatics
Topic: peptidyl transferase center?!
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Views: 1571

peptidyl transferase

Hey there. I have a little problem. :( PTC is an enzyme which catalyzes the peptide formation reaction. It is located in 60s subunit of ribosome. EC 2.3.2.12 . I actually need a pdb file of ptc for my docking issue. how can I find it??

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by Parisa
Tue Nov 05, 2013 10:11 pm
 
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Topic: peptidyl transferase
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peptidyl transferase center?!

Hey there. I have a little problem. :( PTC is an enzyme which catalyzes the peptide formation reaction. It is located in 60s subunit of ribosome. EC 2.3.2.12 . there are some pdb IDs like 3j3b n 3j3f but not for the pure protein. I actually need a pdb file of ...

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by Parisa
Tue Nov 05, 2013 12:12 am
 
Forum: Bioinformatics
Topic: peptidyl transferase center?!
Replies: 1
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