Dictionary » P » Penetrance

Penetrance

Definition

noun

(genetics) The frequency or rate of occurrence, typically in percentage, of a particular trait or condition (e.g. disease) expressed among individuals carrying the same deleterious (or disease-causing) gene.


Supplement

Genetic penetrance describes the likelihood that a particular gene will be expressed and result in a disease.

Penetrance may be:


‘’Compare:’’ expressitivity


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re:

... white color is present - it must be the default phenotype. Thus "white" is null allele of "blue" gene. Lastly, Does complete penetrance imply dominance? If an affected woman mates with a healthy man and the trait she carries the genes for are subject to complete penetrance, ...

See entire post
by Cat
Wed Dec 14, 2011 9:58 pm
 
Forum: Genetics
Topic: Question about basic crossing.
Replies: 5
Views: 3545

Question about basic crossing.

... I thought I could also ask another quick question (not related to this specific topic) here instead of creating a new thread. Does complete penetrance imply dominance? If an affected woman mates with a healthy man and the trait she carries the genes for are subject to complete penetrance, ...

See entire post
by MrJules
Wed Dec 14, 2011 1:01 pm
 
Forum: Genetics
Topic: Question about basic crossing.
Replies: 5
Views: 3545

Re: Multiple Sclerosis symptoms explained in terms of Penetrance

... Sclerosis is not proven to be a genetic disorder. It does show signs of genetic linkage to some degree. This degree of linkage is it's relation to Penetrance and Expressivity. Hutington's disease, for example is a disease that is not considered to be fully penetrant, yet it is highly penetrant ...

See entire post
by Fiorellas
Tue Jul 26, 2011 4:34 pm
 
Forum: Genetics
Topic: Multiple Sclerosis symptoms explained in terms of Penetrance
Replies: 3
Views: 5582

Reduced penetrance vs. multifactorial?

Penetrance is used as a statistical tool to determine the risk of getting ill when you have a particular well-known mutation. So, I don't think it's vital to distinguish if a disorder has reduced penetrance or multifactorial ...

See entire post
by DRT23
Wed Apr 06, 2011 10:34 am
 
Forum: Genetics
Topic: Reduced penetrance vs. multifactorial?
Replies: 1
Views: 2455

Reduced penetrance vs. multifactorial?

Can anybody explain to me how you would be able to distinguish between a disease caused by a single-gene trait with low penetrance and a multifactorial trait? Let's say you were presented with a disease that appeared to run in families but didn't exhibit an obvious pattern of Mendelian ...

See entire post
by Grumbot
Mon Apr 04, 2011 4:23 pm
 
Forum: Genetics
Topic: Reduced penetrance vs. multifactorial?
Replies: 1
Views: 2455
View all matching forum results

This page was last modified 00:08, 26 March 2009. This page has been accessed 11,781 times. 
What links here | Related changes | Permanent link