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Dictionary » P » Penetrance

Penetrance

Definition

noun

(genetics) The frequency or rate of occurrence, typically in percentage, of a particular trait or condition (e.g. disease) expressed among individuals carrying the same deleterious (or disease-causing) gene.


Supplement

Genetic penetrance describes the likelihood that a particular gene will be expressed and result in a disease.

Penetrance may be:


‘’Compare:’’ expressitivity


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Results from our forum


Pedigree Question:

well scott and mary are both healthy and have an infected kid. assuming the trait has 100% penetrance, then they are both heterozygous. assuming the trait is rare (everyone that is from the outside and is not obviously a carrier is homozygous dominant), then scott got ...

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by MrMistery
Thu Mar 05, 2009 2:08 am
 
Forum: Genetics
Topic: Pedigree Question:
Replies: 3
Views: 566

Multiple Sclerosis symptoms explained in terms of Penetrance

this has "homework" written all over it. do you know what penetrance is?

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by MrMistery
Thu Sep 13, 2007 5:51 am
 
Forum: Genetics
Topic: Multiple Sclerosis symptoms explained in terms of Penetrance
Replies: 2
Views: 918

Multiple Sclerosis symptoms explained in terms of Penetrance

... for it actually has clinical symptoms. And if they do, the symptoms are sometimes severe, or sometimes mild. How can you explain this in terms of Penetrance and Expressivity? :?:

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by ritalinn
Wed Sep 12, 2007 12:12 am
 
Forum: Genetics
Topic: Multiple Sclerosis symptoms explained in terms of Penetrance
Replies: 2
Views: 918

pedigrees

dominant: affected persons usually are born out of at least 1affected parent (not when non-penetrance occurs) recessive: affected persons are usually born out of normal parents X-linked: only inherited through the X-chromosome and usually only males are affected (females ...

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by sdekivit
Sun Apr 16, 2006 9:09 am
 
Forum: Genetics
Topic: pedigrees
Replies: 1
Views: 754

Dominance but not majority? Why?!

Even though polydactyly is controlled by a dominant allele it is accompanied by incomplete penetrance hence not observed in majority of the population. The gene doesnot penetrate or show the phenotype associated with the genotype in all the individuals with that genotype.

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by M.Shanti Priya
Thu Feb 02, 2006 9:52 am
 
Forum: Genetics
Topic: Dominance but not majority? Why?!
Replies: 5
Views: 959
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