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Pax gene

(Science: molecular biology) mouse genes that contain a dNA binding domain similar to one in the paired genes of drosophila.

8 pax genes have been identified and most of them are expressed in the nervous system during development. A number of mouse mutations have been found to map to pax genes. For example: undulated, which causes distortions of the vertebral column and sternum results from a point mutations of PAX 1 and is expressed in the sclerotome.