Paracentric inversion

Definition

noun, plural: paracentric inversions

(genetics)

An inversion of a segment of chromosome in which the centromere is not included, and both breaks occur in the single arm of a chromosome.


Supplement

Chromosomal inversion happens when a segment of a chromosome breaks off and reinsert within itself. Inversions may not cause abnormalities in carriers as long as there is no extra or missing genetic information. However, individuals who are heterozygous for an inversion, there is a rise in the production of abnormal chromatids, especially when crossing-over occurs within the span of the inversion.


Word origin: from Gk. para-: beside, near, from, against, contrary to + center.
Compare: pericentric inversion.
See also: centric, inversion, chromosome.


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