Dictionary » P » P-glycoprotein

P-glycoprotein

p-glycoprotein

(Science: cell biology, protein) A family of integral plasma membrane proteins which, when overexpressed, function as adenosine triphosphate-dependent efflux pumps, causing multidrug resistance.

Mammalian p-glycoproteins are encoded by small mdr gene families. There are several isotypes in multiple species.

See: multidrug transporter.


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified 21:16, 3 October 2005. This page has been accessed 5,109 times. 
What links here | Related changes | Permanent link