Dictionary » O » Oxygenase



(Science: enzyme) That catalyses the incorporation of the oxygen of molecular oxygen into organic substrates. Dioxygenases (oxygen transferases) catalyse introduction of both atoms of molecular oxygen, monoxygenases (mixed function oxygenases) introduce one atom, the other becomes reduced to water, so that these enzymes require a second substrate, acting as oxygen donor. Both types are used by bacteria in degradation of aromatic compounds. Dioxygenases all contain iron, for example tryp 2, 3 dioxygenase.

Examples of mono oxygenases are the enzymes that hydroxylate proline and lysine of collagen, using ketoglutarate.

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COX-2 and PGE2

Hi All, From what I understand, cyclo-oxygenase-2 (COX-2) is the enzyme for catalyzing the biosynthesis of prostaglandin E2, and hence the expression of the two entities are closely related. However, is anyone familiar with instances of when ...

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by ezther
Thu Nov 26, 2009 7:32 pm
Forum: Cell Biology
Topic: COX-2 and PGE2
Replies: 1
Views: 1321

Re: bifunctional proteins

It's hard to beat RuBisCO (Ribulose bisphosphate carboxylase/oxygenase) as an extremely abundant example of a protein that catalyzes several reactions (though at a single active site). Also, what about the proteins involved in developmental patterning ...

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by jonmoulton
Tue Nov 03, 2009 4:32 pm
Forum: Molecular Biology
Topic: bifunctional proteins
Replies: 4
Views: 5547

About rubisco

The Rubisco enzyme has both a carboxylase activity and an oxygenase activity - that is, it can bind both CO2 and O2 in the active site. The name derives from R ib u lose b is phophate c arboxylase- o xygenase

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by MrMistery
Sun Feb 03, 2008 5:57 pm
Forum: Cell Biology
Topic: About rubisco
Replies: 2
Views: 1559

About rubisco

... of them state that the rubisco is short for RuBP carboxylase. While there are still some books stating that rubisco is short for RuBP carboxylase/oxygenase. Which of the statement is correct or are the "carboxylase" and "oxygenase" the same compound? Actually, the RuBP should ...

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by qiamond
Sun Feb 03, 2008 4:01 pm
Forum: Cell Biology
Topic: About rubisco
Replies: 2
Views: 1559

What catalyses Carboxylation phase of Dark reaction?

I am confused with the name...its has 2 names.. Is it .. 'RuBP-carboxylase' / 'oxygenase' (or) 'RuBP-carboxylase' / 'RuBP-Oxygenase'

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by satrohraj
Mon Feb 19, 2007 5:00 pm
Forum: Bioinformatics
Topic: What catalyses Carboxylation phase of Dark reaction?
Replies: 0
Views: 2345
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