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Osmotic lysis



The bursting or rupturing of cell membrane due to osmotic movement of water into the cell when the cell is in a hypotonic environment.


Osmotic lysis occurs in animal cells and certain bacteria. When the cells are in a hypotonic environment, the water tends to move into the cell. When the cell membrane cannot hold the excessive influx of water, the cell membrane ruptures.

Osmotic lysis does not occur in plant cells because of the cell wall that contains the turgor pressure.

Word origin: osmotic ยป osmosis + New Latin, from Greek lusis, a loosening.

Synonym: cytolysis.
See also: osmosis.

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Results from our forum

Re: Cell Permability

... solution having high conc. of solute molecule. blood cells have low osmotic potential while water injected has high osmotic potential. thus water enters the cell and results cell lysis.

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by ipsha03
Thu Jul 14, 2011 4:25 pm
Forum: Cell Biology
Topic: Cell Permability
Replies: 6
Views: 23794

Purpose of Mannitol in Mito Isolation

... is the purpose of Mannitol in mitochondrial isolation. I know its an osmotic diuretic so does that mean it dehydrates the mitochondrial before lysis? Thanks Dino

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by dinofernando
Mon Nov 12, 2007 10:50 pm
Forum: Cell Biology
Topic: Purpose of Mannitol in Mito Isolation
Replies: 0
Views: 1267

The Fiber Disease

... of the membrane potential and ionic gradients, and irreversible osmotic swelling leading to the cell wall rupture (lysis), can cause death of the host cell. This pore-forming property has been identified as ...

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by hartuk
Wed Nov 22, 2006 7:28 pm
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6243138

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