Dictionary » O » Opsonization



noun, plural: opsonizations

The process at which opsonins bind to the surface of the antigen so that the antigen will be readily identified and engulfed by phagocytes for destruction


Examples of opsonins are antibody molecules such as the IgM that are capable of activating the complement system to increase the susceptibility of antigens to phagocytosis.


  • opsonisation (British)

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Bubonic plague - yersinia pestis info please

... system to infect its host, it has numerous virulence genes, it has many ways of acquiring iron, it has the ability to resist phagocytosis, and opsonization, and it resides in the lymph node areas as it grows, which creates the buboes. I can refer back to my book and give you more info if you ...

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by mathkilla
Sat Dec 15, 2007 6:57 am
Forum: Microbiology
Topic: Bubonic plague - yersinia pestis info please
Replies: 5
Views: 5219


... they destroy the rest of Strain A within me if this is the case i just read that there are 3 main ways of destryong antigens...like neutralizaion, opsonization and complement...does this mean that in order for the antibodies to bind to these forign objects my system shld hv come across these bugs ...

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by biology_06er
Sun Jun 10, 2007 6:52 am
Forum: Cell Biology
Topic: Antibodies
Replies: 4
Views: 4441

What is the size of an antibody

regarding 1st answer: well that is also unclear since for opsonization to occur the pathogen covered with AB must adhere to the phagocyte via fc receptors on the phgo' (is this correct?) then again the question of size comes up. though I thank you for ...

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by Paragonidae
Fri Mar 16, 2007 6:33 pm
Forum: Molecular Biology
Topic: What is the size of an antibody
Replies: 12
Views: 21074

What is the size of an antibody

... Yes, you are correct, AB's are much smaller than their targets however AB function in 3 ways. 1. Numberous AB will bind a pathogen all over (opsonization) which triggers a immune response .. in which phagocytic cells well be "target" to this pathogen covered in AB. 2. AB can bind ...

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by LilKim
Fri Mar 16, 2007 4:39 pm
Forum: Molecular Biology
Topic: What is the size of an antibody
Replies: 12
Views: 21074

Antigen \ Antibody Interactions

There are two ways on how complement system work. First, by facilitating phagocytosis with opsonization. For instance, the big fragment of complement, C3b, will be bound on the antigen surface. Antibody will recognize this via its Fab. Phagocyte, macrophage and/or PMN ...

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by Dr.Stein
Sat Jan 07, 2006 9:05 am
Forum: Physiology
Topic: Antigen \ Antibody Interactions
Replies: 12
Views: 11700
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