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Operator gene


noun, plural: operator genes

(genetics) A segment of DNA being referred to when the repressor binds to it. As a result, the transcription of certain genes is inhibited.


In the Operon Model, the operator is the gene segment to which a repressor binds. This prevents the RNA polymerase from transcribing certain genes in the operon unit.

Word origin: Latin operā ( rī ) (to work, effect).

Also called:

  • operator (genetics)

See also:

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mRNA transcripts, cis/trans-acting questions

... to metabolize galactose. All of the mutants fail to transcribe the GAL2 gene, which encodes the enzyme for the first step in metabolizing galactose. ... mutations (m1 or m2) is: a. cis-acting? b. trans-acting? c. probably an operator sequence mutation? d. probably a loss-of-function mutation in ...

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by animus31
Fri Nov 09, 2012 11:58 am
Forum: Genetics
Topic: mRNA transcripts, cis/trans-acting questions
Replies: 0
Views: 2131

Repressor always bound to operator

... functioning lac operon, in prokaryotes, repressor protein binds the operator only when lactose concentration is high. However, consider a mutant ... Do you know of any mechanism that allows transcription of lac Z gene even when repressor is always bound to operator sequence?

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by amoeba271
Tue Nov 24, 2009 6:00 am
Forum: Molecular Biology
Topic: Repressor always bound to operator
Replies: 2
Views: 1790

Please Help

... answer. Thanks 1.What is a dominant activator? one copy of an oncogene has been mutated and causes uncontrolled cell growth a proto-oncogene ... repress cell division? Silencer genes Oncogenes Tumor suppressor genes Operator genes Promoter genes 4.The reason v-oncs cause cancer whereas normal ...

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by kpax
Tue Aug 25, 2009 2:33 pm
Forum: Genetics
Topic: Please Help
Replies: 2
Views: 7735


... there are easy tests to determine which major operons regulate your gene... Its probably in your book. Changing the mechanism is pretty easy, just change the operator sequence upstream of the gene. I'm not really sure what the limitations of your ...

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by h2so4hurts
Mon Nov 26, 2007 5:01 pm
Forum: Bioinformatics
Replies: 4
Views: 3346

Re: help with report on Plasmid Properties

... bacteria. we can use them in molecular biology to insert DNA sequences (genes) into other cells or to knock out some genes and see how this affects ... a protein called CRP to form (cAMP,CRP) complex that would bind to the operator domain of Lac o preventing the binding of Lac O repressor and so ...

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by Biologista
Fri Oct 26, 2007 6:19 pm
Forum: Molecular Biology
Topic: Re: help with report on Plasmid Properties
Replies: 4
Views: 3415
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