NOS --> nitric oxide synthase

(Science: enzyme) An enzyme that catalyses the conversion of l-arginine, nADPH, and oxygen to citrulline, nitric oxide, and NADP_.

The enzyme found in brain, but not that induced in lung or liver by endotoxin, requires calcium.There are two isoforms, one constitutive and one activated by calmodulin.

Chemical name: L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)

Registry number: EC

Acronym: NOS

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