nitric oxide synthase
(Science: enzyme) An enzyme that catalyses the conversion of l-arginine, nADPH, and oxygen to citrulline, nitric oxide, and NADP_.
The enzyme found in brain, but not that induced in lung or liver by endotoxin, requires calcium.There are two isoforms, one constitutive and one activated by calmodulin.
Chemical name: L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)
Registry number: EC 188.8.131.52