Dictionary » N » Nondisjunction

Nondisjunction

Definition

noun

(In mitosis) The failure of sister chromatids to separate during and after mitosis.

(In meiosis) The failure of homologous chromosomes to segregate or to separate during and after meiosis.


Supplement

This could result to a condition wherein the daughter cells have an abnormal number of chromosomes; one cell having too many chromosomes while other cell having none.

Examples of nondisjunction:


Related forms: nondisjunctional (adjective).
Related terms: meiotic nondisjunction.

Compare: disjunction.
See also: anaphase.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Using Colchicine for Polyploids

So I was wondering... Colchicine is used to create polyploid plants. It acts as a mitotic spindle poison which can cause nondisjunction of the entire genome. What I was wondering was that if you were to treat a seed with a colchicine solution, is the disjunction of the entire genome ...

See entire post
by plasmodesmata11
Tue Jul 19, 2011 10:50 pm
 
Forum: Genetics
Topic: Using Colchicine for Polyploids
Replies: 0
Views: 1711

Aneuploidy and Mosaicism

... will lead an organism to unwanted results? Do chromosomes of the same type code for the same genetic information? 2. Mosaicism happens if nondisjunction happens during cell division of an embryo. If a normal disomic cell undergoes mitosis, and one of the outcome is a trisomic cell, then ...

See entire post
by Procon1234
Sun Jan 09, 2011 3:23 pm
 
Forum: Genetics
Topic: Aneuploidy and Mosaicism
Replies: 4
Views: 2410

Regarding Mutation

... Down syndrome. It is the cause of 2–3% of observed cases of Down syndrome. 95% of the observed cases of Trisomy 21 is anueploidy caused by meiotic nondisjunction events in the parental gametes (88% in the female gamete, and 7% in the male gamete).

See entire post
by kolean
Sun Jul 12, 2009 8:37 pm
 
Forum: Genetics
Topic: Regarding Mutation
Replies: 5
Views: 6170

GOT A QUESTION

... The karyotype was taken from a man that had XYY disorder. The question was how does one go about inheriting the XYY disorder. I explained about nondisjunction during meiosis and subsequent formation of gametes. And also, I think the XYY disorder is actually not necessarily inherited genetically, ...

See entire post
by biotchr
Mon Mar 05, 2007 5:00 am
 
Forum: Human Biology
Topic: GOT A QUESTION
Replies: 2
Views: 1916

Down syndrome

... you need to determine the chance that a second child would suffer from the condition? My answers: a The most likely cause of trisomy-21 would be nondisjunction b/c firstly it is her sixth child (suggesting that it is not within her phenotype), secondly her age. b ?????

See entire post
by student12
Tue Aug 15, 2006 8:53 am
 
Forum: Genetics
Topic: Down syndrome
Replies: 1
Views: 1516
View all matching forum results

This page was last modified 08:55, 29 October 2008. This page has been accessed 160,272 times. 
What links here | Related changes | Permanent link