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Nmda

NMDA --> N methyl D aspartate receptor

(Science: physiology) glutamate receptor sub type (see excitatory amino acids). N methyl D aspartate receptor channels seem to be potentiated by intracellular arachidonic acid.

Acronym: NMDA


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How to go about creating a stably-transfected cell line

... differentiate them into neurons using retinoic acid. I wish to create a stable clone expressing a GFP-fusion neurotransmitter receptor, of either NMDA-R or AMPA-R, but I am not very clear about what should be done. First off, how should I go about getting a suitable expression vector? I.e., what ...

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by JustinNg
Mon Sep 17, 2012 9:26 am
 
Forum: Molecular Biology
Topic: How to go about creating a stably-transfected cell line
Replies: 1
Views: 1873

Quick question on genes - thanks!

... and 20 of them make every protein in the body! Splicing also varies between cells - so some might want a AMPA receptor for glutamate and another a NMDA receptor - and so there will be differential splicing of the same gene in each of these cells. So the exons are being used for different codes ...

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by Babybel56
Thu Apr 28, 2011 9:33 am
 
Forum: Cell Biology
Topic: Quick question on genes - thanks!
Replies: 4
Views: 4286

The Fiber Disease

... of Neuroscience Research, vol. 30, pp. 300-07, 1991. [6] R. D. Fields, C. Yu, and P. G. Nelson, "Calcium, network activity, and the role of NMDA channels in synaptic plasticity in vitro," Journal of Neuroscience, vol. 11, pp. 134-46, 1991. [7] A. S. Curtis and P. Clark, "The effect ...

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by Nadas Moksha
Sat Oct 28, 2006 3:28 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5578119

Curious... about the human brain...

... firing impulses even after the signal that came from a synapse is over. It is pretty complex and it involves some special receptors - AMPA and NMDA. I am lazy and won't explain it here. Google it if you want. 2. Define intelligence. Nobody has ever did that. What we do know is that the young ...

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by MrMistery
Sat Sep 02, 2006 5:22 pm
 
Forum: Human Biology
Topic: Curious... about the human brain...
Replies: 12
Views: 4710


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