Dictionary » N » Nitroglycerin

Nitroglycerin

Nitroglycerin

(Science: chemistry) A liquid appearing like a heavy oil, colourless or yellowish, and consisting of a mixture of several glycerin salts of nitric acid, and hence more properly called glycerin nitrate.

It is made by the action of nitric acid on glycerin in the presence of sulphuric acid. It is extremely unstable and terribly explosive. A very dilute solution is used in medicine as a neurotic under the name of glonion.

A great number of explosive compounds have been produced by mixing nitroglycerin with different substances; as, dynamite, or giant powder, nitroglycerin mixed with siliceous earth; lithofracteur, nitroglycerin with gunpowder, or with sawdust and nitrate of sodium or barium; Colonia powder, gunpowder with nitroglycerin; dualin, nitroglycerin with sawdust, or with sawdust and nitrate of potassium and some other substances; lignose, wood fibre and nitroglycerin.

pharmacologic action: relaxes smooth muscle - dilates veins, dilates coronary arteries, reduces left ventricular filling pressure, lowers systemic vascular resistance, decreases myocardial oxygen demand.

uses: treat angina pectoris.

dose: One tablet (0.3 to 624

0.4 mg) sublingual, may repeat twice at 5 minute intervals intravenous infusion: 0.5 - 2 mcg/kg per min.

potential complications: May cause hypotension, especially if hypovolemic; headache is common.

alternative forms: nitroglycerine.

Origin: Nitro- _ glycerinn.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re: Molecules entering the bloodstream from skin absorption

Hydrophobic substance does get through skin, that how a lot of medications work, Eg, Nicotine, and Nitroglycerin for heart attacks, Similarity a lot of toxins work the same way (seen them in action thrillers) , Does that help?

See entire post
by david23
Sat Jul 14, 2012 1:07 am
 
Forum: Human Biology
Topic: Molecules entering the bloodstream from skin absorption
Replies: 2
Views: 14675

Help! Convert mg/ml to mg/kg

... approx 30g each (+a little extra just in case) I was given this information. C1= 5mg/ml V1= .8ml C2= 1mg/ml V2=4 I need to add saline to the nitroglycerin to get the proper concentration, dose and volume. I'm lost...

See entire post
by sadieg
Thu Oct 28, 2010 12:14 am
 
Forum: Molecular Biology
Topic: Help! Convert mg/ml to mg/kg
Replies: 5
Views: 11596

Help! Convert mg/ml to mg/kg

Okay, I have nitroglycerin at 5mg/ml (in liquid form). My mice need a dose of 10mg/kg. I have 8 mice weighing approximately 30g. How do I figure out how to dilute to the proper concentration and volume? I think I need to use C1V1=C2V2, ...

See entire post
by sadieg
Wed Oct 27, 2010 5:48 pm
 
Forum: Molecular Biology
Topic: Help! Convert mg/ml to mg/kg
Replies: 5
Views: 11596

Headaches

Infrequent exposure to high doses of nitroglycerin can cause severe headaches known at NG head, these headaches can be severe enough to incapcitate some people, however, humans develop a tolerance and addiction to nitroglycerin after long-term ...

See entire post
by mith
Thu Jan 11, 2007 2:50 pm
 
Forum: Human Biology
Topic: Headaches
Replies: 20
Views: 8027

Nitroglycerine

Hang on, what you mean by inhaling in astma is NOT nitroglycerin, its either corticosteroids as antiinflammatory agent for chronic treatment and adrenergic receptor agonists (albuterol etc) for acute treatment; these are used as BRONCHOdilators. Nitroglycerin ...

See entire post
by weesper
Tue Aug 15, 2006 10:05 am
 
Forum: Human Biology
Topic: Nitroglycerine
Replies: 4
Views: 2482
View all matching forum results

This page was last modified 18:34, 10 April 2007. This page has been accessed 3,281 times. 
What links here | Related changes | Permanent link