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Negative regulation


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Graphs depicting qPCR fold change

... a scale from 0 to whatever, where values between 0 and 1 represent down-regulation, and values >1 represent up-regulation. But the problem with ... appreciate the extent of down-regulation. 2. Using inverse values where negative values (<-1) represent down-regulation and positive values (>+1) ...

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by loudowns
Mon Jun 30, 2014 4:37 pm
 
Forum: Molecular Biology
Topic: Graphs depicting qPCR fold change
Replies: 0
Views: 600

Problem with the normalization of PCR Ct values

... gene mRNA" ? Finally if I want to present the data as 2^ΔCt, negative values mean down-regulation and positive values up-regulation? If you could suggest any literature dealing with ...

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by Tzia
Wed May 01, 2013 8:48 pm
 
Forum: Molecular Biology
Topic: Problem with the normalization of PCR Ct values
Replies: 5
Views: 4262

Re: Theories - Origin of Life

... touched. But, just to nail down this point, study this paper about the regulation by and of p53 master sensor of stress. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857175/ Tied Up in Loops: Positive and Negative Autoregulation of p53 In part it states Of these, p53/mdm2 is the master autoregulation ...

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by scottie
Wed Feb 22, 2012 8:12 pm
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929089

Re: Theories - Origin of Life

... often exhibit functional roles, such as gene expression, gene regulation, generation of genetic (antibody, antigenic, and other) diversity. ... Is this a positive argument for Darwinian macro evolution or simply a negative one against design.? Could you clarify please.

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by scottie
Sun Dec 18, 2011 3:40 pm
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929089

Re: Theories - Origin of Life

... systems in response to a major evolutionary challenge. The cellular regulation of natural genetic engineering automatically imposes a punctuated ... non-functional. In this sense, natural selection plays an essentially negative role, as postulated by many early thinkers about evolution (e.g. ...

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by scottie
Mon May 23, 2011 8:28 pm
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929089
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