A feedback in which the system responds in an opposite direction to the perturbation.
It is a self-regulatory system in which it feeds back to the input a part of a system’s output so as to reverse the direction of change of the output.
The process reduces the output of a system in order to stabilize or re-establish internal equilibrium. There are several negative feedback in biological system to regulate and maintain homeostasis. Some of which are the regulation of hormone synthesis, blood glucose levels, body temperature, and baroflex in blood pressure.