Nedocromil

nedocromil

(Science: chemical) A pyranoquinolone derivative that prevents asthma attacks. It affects the function and inhibits the release of inflammatory mediators from tissue mast cells, inhibits recruitment of other inflammatory cells (such as eosinophils and neutrophils) into the airway epithelium, inhibits both immediate and late bronchoconstriction, and decreases bronchial hyperresponsiveness. It is not a bronchodilator and is not useful in the treatment of acute asthma.

Pharmacological action: anti-allergic agents, anti-asthmatic agents, anti-inflammatory agents.

Chemical name: 4H-Pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-

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