Nadph dehydrogenase quinone
NADPH dehydrogenase (quinone)
(Science: enzyme) A flavoprotein that reversibly catalyses the oxidation of nADH or nADPH by various quinones and oxidation-reduction dyes. Since the enzyme is a part of the mitochondrial respiratory chain, defects or deficiencies of this enzyme are an important cause of neurological diseases such as parkinsonism. It may have a protective effect against cancer caused by quinones or their metabolic precursors. The enzyme is inhibited by dicoumarol, capsaicin, and caffeine.
Chemical name: NAD(P)H:(quinone-acceptor) oxidoreductase
Registry number: EC 220.127.116.11