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Myoglobin

myoglobin

(Science: physiology) protein (17.5 kD) found in red skeletal muscle. It was the first protein for which the tertiary structure was determined by x-ray diffraction, by J.C.Kendrew's group working on sperm whale myoglobin.

It is a single polypeptide chain of 153 amino acids, containing a haem group bonded via its ferric iron to two histidine residues. It binds oxygen noncooperatively and has a higher affinity for oxygen than haemoglobin at all partial pressures. In capillaries oxygen is effectively removed from haemoglobin and diffuses into muscle fibres where it binds to myoglobin which acts as an oxygen store.


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Aerobic respiration

Explain, in general terms, aerobic cellular respiration as it takes place in a skeletal muscle, and describe the role myoglobin plays in this reaction.

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by AlysseAllarie
Fri Jan 07, 2011 3:31 am
 
Forum: Human Biology
Topic: Aerobic respiration
Replies: 1
Views: 1332

Change in distal his in hemoglobin

... structural features that are directly related to this function. Furthermore, we have discussed the importance of the distal His (His64) in myoglobin with respects to carbon monoxide binding. Hemoglobin subunits also each have a distal His (His58 for α and His63 for β) that functions in ...

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by tntran
Fri Oct 16, 2009 3:09 pm
 
Forum: Molecular Biology
Topic: Change in distal his in hemoglobin
Replies: 1
Views: 1551

Re:

... genes are produced by several mechanisms which include gene duplication, random mutations, promoter mutations and etc. For example, hemoglobin and myoglobin are both proteins in our blood that carry oxygen but deliver that oxygen under different conditions. Hemoglobin delivers that oxygen as needed ...

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by MolecularBioFTW
Wed Sep 30, 2009 5:50 pm
 
Forum: Evolution
Topic: Natural selection is proven wrong
Replies: 247
Views: 575465

Re: The Effect of pH on the Plant Cell Membrane

Sorry. :oops: Could have sworn it said "meat", but clearly it says "beet". My mistake; and all that stuff about myoglobin isn't relevant. But I still don't quite understand what exactly was done--be it beet or meat slices.

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by blcr11
Wed Oct 08, 2008 5:24 pm
 
Forum: Molecular Biology
Topic: The Effect of pH on the Plant Cell Membrane
Replies: 6
Views: 15406

Re: The Effect of pH on the Plant Cell Membrane

... is probably what you meant to say in the title, I would guess. The red pigment in red meats comes mostly from a hemoglobin-like molecule called myoglobin. Myoglobin is the intracellular oxygen carrier and doesn't circulate like hemoglobin does with the RBCs. So long as the muscle cell membranes ...

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by blcr11
Wed Oct 08, 2008 1:00 pm
 
Forum: Molecular Biology
Topic: The Effect of pH on the Plant Cell Membrane
Replies: 6
Views: 15406
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