Dictionary » M » Myc



(Science: oncogene) This proto-oncogene causes cancers (carcinomas and sarcomas) and is found in the avian myelocytomatosis virus. It has been identified in several avian tumours, and encodes a nuclear protein with a leucine zipper motif.

If translocated, it can cause burkitt's lymphoma, if amplified, it can cause lung, breast, and cervical carcinomas. It is found in both chickens and has an analogue in humans which is located on the long arm of chromosome 8.

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Can s/one help me to solve the problem

... I really need your help.I am doing the linker-ligated vector construction. I have a 7 kbase -plasmid with the AsisI cutting site. I design the 3 Myc linker with some nucleotides change in the 5 prime end and 3 prime end so that it can ligate to the Asis I site. I cut my plasmid with AsisI with ...

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by huyenkobe
Fri Dec 24, 2010 4:13 am
Forum: General Discussion
Topic: Can s/one help me to solve the problem
Replies: 0
Views: 1179

Re: Which came first the DNA, RNA or protein

... synthesized by skeletal cells, found in most species, that controls proliferation, cellular differentiation, and other functions in most cells. B. Myc produces DNA binding protein http://www.answers.com/topic/myc-2 myc = Any of a group of vertebrate oncogenes whose product, a DNA binding protein, ...

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by Dov Henis
Mon Mar 22, 2010 9:23 pm
Forum: Molecular Biology
Topic: Which came first the DNA, RNA or protein
Replies: 64
Views: 53128

Re: Human aging

... in next generation..I can't find the exact page..but the book is Essentials of stem cell biology by Robert Lanza et al. Also oncogenes like Myc bind to promoter of key subunit of telomerase and increase number of divisions etc...

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by zami'87.
Sat Jan 23, 2010 3:09 pm
Forum: Genetics
Topic: Human aging
Replies: 20
Views: 18708

Please Help

... than are c-oncs All of these 5.Which of the following is the best example of a tumor-suppressor gene? The RB gene involved in retinoblastoma C-myc involved in Burkitt's lymphoma. Philadelphia chromosome in chronic myelogenous leukemia Platelet-derived growth factor (PDGF) C- ras involved in ...

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by kpax
Tue Aug 25, 2009 2:33 pm
Forum: Genetics
Topic: Please Help
Replies: 2
Views: 7679

Re: is it possible to knockdown a gene in a living adult now

... a drug eluting stent that uses a PPMO (peptide-conjugated morpholino phosphorodiamidate oligomer)-based RNA therapeutic agent aimed at silencing C-MYC, one of the genes responsible for causing arteries to reclose after stenting (restenosis). <snip> ------------------------------------------ ...

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by jonmoulton
Tue Nov 18, 2008 6:05 pm
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 15144
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