Mutations

All genes are necessary and required.. that's the general rule of genomics. It's mutations in genes that affect the "good" or "bad" effects of the gene in particular. Considering the pathway the p21 gene is in, a mutation in it would be a negative ...

See entire post

Hi there, what exactly genome wide screening? I guess it is when you look at genes for mutations etc? How is it done? Thanks in advance, b_06er

See entire post

... the basic step of evolution. One can evolve new traits without genetic mutation (eg quantitative traits); nevertheless most individuals have a few mutations anyway. Let me give you an example from the 1950s (if I recall correctly). It was shown that two populations of Drosophila could be selected ...

See entire post

... risk to sound stupid..but if RNA is responsible for paramutation(It sounds very possible,agree as it can have enzymatic activity) than mutations in that RNA could make exceptions from paramutation rule. So two genes are involved? This reminds me on prions,as prion protein originates ...

See entire post

Well mutations are definitely a way to create genetic diversity, yes. One could wrote a PhD thesis on the subject, or more (as I and many friend from the laab I studied did). An example of what happens in bacteria here . Good ...

See entire post