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Mutation rate

mutation rate

The frequency with which a particular mutation appears in a population or the frequency with which any mutation appears in the whole genome of a population. Normally the context makes the precise use clear.

See: fluctuation analysis.

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Hyperadrenergic POTS

... (Postural Orthostatic Tachycardia Syndrome) is when a person’s heart rate speeds up 30 beats per minute or more without much change in blood pressure ... with hyperadrenergic POTS. These individuals have a single point mutation in the norepinephrine transporter (NET). The resultant inability ...

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by rmorrison
Wed Mar 19, 2014 5:38 pm
Forum: Human Biology
Topic: Hyperadrenergic POTS
Replies: 0
Views: 6044

Re: Re:

... the more they accumulate the more opportunity there is for compensatory mutations to bring the basic fitness level back to a kind of running equilibrium ... We have this intuition that natural selection is working at a fixed rate. If the mutation rate increases beyond the rate of natural selection, ...

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by wildfunguy
Sat Oct 19, 2013 9:18 pm
Forum: Evolution
Topic: Beneficial mutations vs harmful
Replies: 12
Views: 15660


2) if there is about one mutation per new being in humans (may be much higher in other organisms) and you have ... basis of "genetic drift". Another implication: the deleterious mutation rate (more than 2) is high. The real force of the original question of the thread is ...

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by ChrisHoStuart
Tue Oct 15, 2013 2:19 pm
Forum: Evolution
Topic: Beneficial mutations vs harmful
Replies: 12
Views: 15660

Why must we avert the genome of Eden?

... avert such complex LUA, but even the best efforts (HGT) in doing so generate more problems than solutions. From what I gathered it seems traces of ... the official view, these genes are produced independently by parallel mutations. Interestingly in the case of the broken vitamin-C gene, the homologous ...

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by Hunor
Mon Sep 23, 2013 12:08 am
Forum: Evolution
Topic: Why must we avert the genome of Eden?
Replies: 6
Views: 14528

mutation-selection balance

... death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, ... of the lethal allele in the population, is equal to μ, the mutation rate (p = μ). We can use the same principles to predict the relationship ...

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by Monco
Mon Mar 04, 2013 10:41 pm
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 4035
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