Dictionary » M » Mutation

Mutation

Definition

noun, plural: mutations

(general)

A change in or the process of changing, e.g. nature, form or quality.

(genetics)

(1) A permanent, heritable change in the nucleotide sequence in a gene or a chromosome; the process in which such a change occurs in a gene or in a chromosome.

(2) A mutant, or an individual exhibiting such a change.


Supplement

In genetics, mutation may be small scale (affecting the nucleotide sequence of a gene) or large scale (involving a change in the chromosome). It may arise from faulty deletions, insertions, or exchanges of nucleotides in the genetic material, as caused by exposure to ultraviolet or ionizing radiation, chemical mutagens, viruses, etc. Such a change may result in the creation of a new character or trait.


Word origin: Mutatio from mutare = to change (biology) an organism that has characteristics resulting from chromosomal alteration.

Related forms: mutant (noun), mutate (verb).
Related terms: addition mutation, conditional mutation, deletion mutation, forward mutation, frameshift mutation, homeotic mutation, lethal mutation, missense mutation, mutation frequency, mutation rate, point mutation, substitution mutation.


User Contributions / Comments:

  • Mutation is essential to evolution. They introduce new traits in a population,change allele frequencies and include changes in the DNA sequences.

(~Dlee7283) Mutations introduce new traits in a population,change allele frequencies and include changes in the DNA sequences.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


BRC-ALT Tyrosine Kinase

... problem in leukemia because it is transcribed more often when on Chromosome 22 or if it is simply just always in the active configuration due the mutation, or both? I have looked on access medicine and watched Kevin Ahern's lectures on youtube and both causes are mentioned, but not in the same ...

See entire post
by tmbirkhead
Thu Aug 14, 2014 1:22 am
 
Forum: Molecular Biology
Topic: BRC-ALT Tyrosine Kinase
Replies: 0
Views: 202

Re:

... HI ! :D I have noticed that Persian cats are very flat face and nose, and have changed a lot in a short time, it's true. How is this obtained? A mutation caused them to have this type of face? Or were selecting cats with a little more flat face, gradually to get one with a very flat face?

See entire post
by Goldentiger
Mon Jul 07, 2014 5:32 pm
 
Forum: Zoology Discussion
Topic: Examples of Mutations ?
Replies: 4
Views: 628

Hyperadrenergic POTS

... neuropathic POTS. A specific genetic abnormality has been identified in a kindred with hyperadrenergic POTS. These individuals have a single point mutation in the norepinephrine transporter (NET). The resultant inability to adequately clear norepinephrine produces a state of excessive sympathetic ...

See entire post
by rmorrison
Wed Mar 19, 2014 5:38 pm
 
Forum: Human Biology
Topic: Hyperadrenergic POTS
Replies: 0
Views: 2636

Polymorphism and Mutation

Just about numbers. A mutation is a change to a single individual that may or may not be propagated. For example a single point mutation where a base is replaced or deleted from a strand of DNA. This may cause the individual some discomfort ...

See entire post
by Babybel56
Wed Mar 05, 2014 3:39 am
 
Forum: Molecular Biology
Topic: Polymorphism and Mutation
Replies: 2
Views: 1689

Polymorphism and Mutation

What is the difference between Gene Polymorphism and Gene Mutation :?: :?: :?: please give a clear concept. :|

See entire post
by Helics
Tue Mar 04, 2014 4:33 pm
 
Forum: Molecular Biology
Topic: Polymorphism and Mutation
Replies: 2
Views: 1689
View all matching forum results

This page was last modified 23:19, 14 December 2009. This page has been accessed 201,831 times. 
What links here | Related changes | Permanent link