Dictionary » M » Mutation

Mutation

Definition

noun, plural: mutations

(general)

A change in or the process of changing, e.g. nature, form or quality.

(genetics)

(1) A permanent, heritable change in the nucleotide sequence in a gene or a chromosome; the process in which such a change occurs in a gene or in a chromosome.

(2) A mutant, or an individual exhibiting such a change.


Supplement

In genetics, mutation may be small scale (affecting the nucleotide sequence of a gene) or large scale (involving a change in the chromosome). It may arise from faulty deletions, insertions, or exchanges of nucleotides in the genetic material, as caused by exposure to ultraviolet or ionizing radiation, chemical mutagens, viruses, etc. Such a change may result in the creation of a new character or trait.


Word origin: Mutatio from mutare = to change (biology) an organism that has characteristics resulting from chromosomal alteration.

Related forms: mutant (noun), mutate (verb).
Related terms: addition mutation, conditional mutation, deletion mutation, forward mutation, frameshift mutation, homeotic mutation, lethal mutation, missense mutation, mutation frequency, mutation rate, point mutation, substitution mutation.


User Contributions / Comments:

  • Mutation is essential to evolution. They introduce new traits in a population,change allele frequencies and include changes in the DNA sequences.

(~Dlee7283) Mutations introduce new traits in a population,change allele frequencies and include changes in the DNA sequences.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


mutation-selection balance

... and Bamshad: Consider, for example, a dominant disease that results in death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, he or she contributes no genes to the next generation. Each time mutation ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 59

mutations and dependencies

The literature for mutation in germ line cells are on the internet. Anyway if someones interested he has a talk on youtube 'Numerical simulation predicts human extinction'. Laterz.

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by jinx25
Sun Feb 24, 2013 7:04 am
 
Forum: Evolution
Topic: mutations and dependencies
Replies: 17
Views: 844

Re: mutations and dependencies

... as to why genome sequencing results are consistent with inferences based on the fossil record? Now I will quote one of the linked articles. bad mutations are physically linked to good mutations,2 so that they cannot be separated in inheritance (to get rid of the bad and keep the good). The result ...

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by wildfunguy
Sat Feb 23, 2013 3:50 pm
 
Forum: Evolution
Topic: mutations and dependencies
Replies: 17
Views: 844

Re: mutations and dependencies

the lack of evidence for something=evidence for it Nobody could say that, since it's nonsense. One mutation could (potentially) kill you, but dozens of others do not. Moreover, our genome is optimized after milions of years of evolution. How much more would you like to optimize ...

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by JackBean
Thu Feb 21, 2013 3:59 pm
 
Forum: Evolution
Topic: mutations and dependencies
Replies: 17
Views: 844

mutations and dependencies

... appreciate some commentary. I recently learned about epistasis and genetic heterogeneity . Apparently, you can get similar phenotypic results from mutations in different genes that are part of the same biological pathway. To me, this seems similar to computer programs that have depencies. If a ...

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by wildfunguy
Sun Feb 17, 2013 5:58 pm
 
Forum: Evolution
Topic: mutations and dependencies
Replies: 17
Views: 844
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