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Mutagens

mutagens

chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.


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Human aging

... cells I do not know. I'd guess the rate of mutation is dependent on the given cell's exposure to environmental agents, metabolic stress, mutagens or such other outside factors. Furthermore, what genes are active in the cell determines the effects of the mutations: a (specialised?) cell ...

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by biohazard
Wed Jan 14, 2009 12:04 pm
 
Forum: Genetics
Topic: Human aging
Replies: 17
Views: 1881

Re: When do mutations occur?

... mitosis, and replication. Exposure to physical or chemical insults from the environment (e.g. short-wave UV irradiation, exposure to intercalating mutagens, etc.) and some biological insults, such as infection by papillomavirus, may either independently cause mutations or increase the probability ...

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by jonmoulton
Tue Nov 04, 2008 5:31 pm
 
Forum: Molecular Biology
Topic: When do mutations occur?
Replies: 17
Views: 2737

Re: about Br-ATP

... kinds of things. The base is derivatized at one or another postion depending on the nucleotide. Sometimes halogenated nucleotides are used as mutagens or as a density label (bromo-deoxy uridine, for example) People who like to do crystal structures of nucleic acids, either of oligonucleotides ...

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by blcr11
Wed Mar 05, 2008 3:10 pm
 
Forum: Molecular Biology
Topic: about Br-ATP
Replies: 1
Views: 355

DNA damage

... that physically bind DNA and protect it from U.V. light or R.O.S.s in the genome proper, sorry. Rather, I think the way the cell deals with these mutagens is to try to correct DNA damage after the fact. The reason for this is that proteins can be damaged by U.V. light and R.O.S.s, too, so it is ...

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by G-Do
Tue Jan 02, 2007 2:15 am
 
Forum: Molecular Biology
Topic: DNA damage
Replies: 5
Views: 797

CHEMICAL GENETICS

what is the biological pathway of an ordinary cell in becoming to a carcinogenic one by some mutagen?is it possible to deactivate the potential mutagens by chemical means?can present nano bio technology be effectively used in this regard?can we pre assume what are the cell potential candidate ...

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by JOY
Sat Nov 11, 2006 11:20 am
 
Forum: Genetics
Topic: CHEMICAL GENETICS
Replies: 1
Views: 539
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