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muscimol

(Science: chemical) 5-(aminomethyl)-3-isoxazolol. Neurotoxic isoxazole isolated from amanita muscaria and a. Phalloides and also obtained by decarboxylation of ibotenic acid. It is a potent agonist at gaba-a receptors and is used mainly as an experimental tool in animal and tissue studies.

Pharmacological action: gaba agonists.

Chemical name: 3(2H)-Isoxazolone, 5-(aminomethyl)-