Mosaicism

Definition

noun

A condition wherein two or more cell populations with different genotypes exist in an organism, derived from a single zygote, as a result of experimental manipulation or to faulty distribution of genetic material during mitosis.


Supplement

For example is the rare condition wherein some cells of the body of a patient have XX chromosomes while other cells have XY chromosomes. Another example is the 46/47 XY/XXY mosaic in which the individual contains two sets of cell populations: (1) a population of cells with the normal 46 number of chromosomes and XY genetic constitution, and (2) a cell population with 47 chromosomes and XXY genetic consititution.


Word origin: mosaic + -ism

Synonym:

Compare: chimerism

See also: sex chromosome

Related term:


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified on 7 February 2009, at 02:17. This page has been accessed 7,110 times. 
What links here | Related changes | Permanent link