Dictionary » M » Mosaicism

Mosaicism

Definition

noun

A condition wherein two or more cell populations with different genotypes exist in an organism, derived from a single zygote, as a result of experimental manipulation or to faulty distribution of genetic material during mitosis.


Supplement

For example is the rare condition wherein some cells of the body of a patient have XX chromosomes while other cells have XY chromosomes. Another example is the 46/47 XY/XXY mosaic in which the individual contains two sets of cell populations: (1) a population of cells with the normal 46 number of chromosomes and XY genetic constitution, and (2) a cell population with 47 chromosomes and XXY genetic consititution.


Word origin: mosaic + -ism

Synonym:

Compare: chimerism

See also: sex chromosome

Related term:


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re:

[quote="Darby"]"The most common reason for different color eyes is mosaicism (the "old" one, not the new one associated with chimeras ),...." I find the explanation of human chimeras quite fascinating as it infers that "nature" ...

See entire post
by Annij
Sun Nov 03, 2013 5:04 am
 
Forum: Human Biology
Topic: two different color eyes
Replies: 141
Views: 277453

Re: two different color eyes

... also of hair or skin. Heterochromia is a result of the relative excess or lack of melanin (a pigment). It may be inherited, or caused by genetic mosaicism, disease or injury.[1] Eye color, specifically the color of the irises, is determined primarily by the concentration and distribution of melanin.[2][3][4] ...

See entire post
by CaitlynLillis
Fri Dec 09, 2011 10:14 pm
 
Forum: Human Biology
Topic: two different color eyes
Replies: 141
Views: 277453

Aneuploidy and Mosaicism

Since mosaicism involves a limited population of cells using limited groups of genes, the effect of chromosome 21 would be really variable.

See entire post
by Darby
Sat Jan 15, 2011 10:17 pm
 
Forum: Genetics
Topic: Aneuploidy and Mosaicism
Replies: 4
Views: 2770

Aneuploidy and Mosaicism

... more or less chromosomes will lead an organism to unwanted results? Do chromosomes of the same type code for the same genetic information? 2. Mosaicism happens if nondisjunction happens during cell division of an embryo. If a normal disomic cell undergoes mitosis, and one of the outcome is ...

See entire post
by Procon1234
Sun Jan 09, 2011 3:23 pm
 
Forum: Genetics
Topic: Aneuploidy and Mosaicism
Replies: 4
Views: 2770

Re: two different color eyes

... melanocytes are the cause of heterochromia iridium (having two different coloured eyes) , but it is also due to hereditary genetics, genetic mosaicism, and or because of disease or injury. I'm doing a project on it in Chemistry 11.

See entire post
by Melanin93
Fri Jun 11, 2010 12:33 am
 
Forum: Human Biology
Topic: two different color eyes
Replies: 141
Views: 277453
View all matching forum results

This page was last modified 02:17, 7 February 2009. This page has been accessed 6,102 times. 
What links here | Related changes | Permanent link