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Monoclonal antibody

monoclonal antibody

(Science: immunology molecular biology) A substance, usually a protein, which can be synthsised in the laboratory in pure form by a single clone (population) of cells.

These antibodies can be made in large quantities and have a specific affinity for certain target molecules called antigens which can be found on the surface of cells and those that are malignant.

monoclonal antibodies are currently being investigated as a possible form of cancer treatment although their benefit has not be fully proven.


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Anti idiotype antibody

If i raise an antibody in a particular strain of mouse (BALB/c) with an antigen, the i collect that antibody ( monoclonal) and inject it into another BALB/c mouse. Would i get anti-idiotype, isotype or allotype antibody ...

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by Microbuddy
Wed Feb 18, 2015 6:15 pm
 
Forum: Cell Biology
Topic: Anti idiotype antibody
Replies: 0
Views: 200

Stem Cells

... be used to track down these cells, either with flow cytometry or other monoclonal antibody/fluorescence-based assays. The problem is that the stem cells are usually very rare ...

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by biohazard
Tue May 14, 2013 6:56 am
 
Forum: Molecular Biology
Topic: Stem Cells
Replies: 4
Views: 3143

ELISA

ELISA protocols changes according to the spesific antigen or the antibody investigated. It also changes according the antigen or antibody whether you use monoclonal or policlonal. What are you investigating specifically? And for what purpose do ...

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by gislab03
Sat May 04, 2013 2:11 pm
 
Forum: Molecular Biology
Topic: ELISA
Replies: 1
Views: 1529

Re: Re:

... most certainly be developed. If I had to guess, I would perhaps go for monoclonal antibody-based treatments to be the next big thing. The specific nature of antibodies would ...

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by Ahsmeah
Tue Feb 05, 2013 10:10 pm
 
Forum: Physiology
Topic: Cancer = Mutation: Stopping Mutation Would Cure Cancer?
Replies: 7
Views: 15452

Re: Re:

... most certainly be developed. If I had to guess, I would perhaps go for monoclonal antibody-based treatments to be the next big thing. The specific nature of antibodies would ...

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by biohazard
Tue Feb 05, 2013 1:23 pm
 
Forum: Physiology
Topic: Cancer = Mutation: Stopping Mutation Would Cure Cancer?
Replies: 7
Views: 15452
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