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Monoclonal antibody

monoclonal antibody

(Science: immunology molecular biology) A substance, usually a protein, which can be synthsised in the laboratory in pure form by a single clone (population) of cells.

These antibodies can be made in large quantities and have a specific affinity for certain target molecules called antigens which can be found on the surface of cells and those that are malignant.

monoclonal antibodies are currently being investigated as a possible form of cancer treatment although their benefit has not be fully proven.


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Antibodies to ID mouse neutrophils and monocytes

What about this thing: - NIMP-R14 The monoclonal antibody NIMP-R14 has been succesfully used to stain neutrophils for fluorescent activated cell sorting ...

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by DoctorStein
Sat Jul 12, 2008 7:35 am
 
Forum: Cell Biology
Topic: Antibodies to ID mouse neutrophils and monocytes
Replies: 7
Views: 1131

Production of Remicade in Animal Cell Culture

... (infliximab) itself, I'm not too familiar with it, but afaik it is a monoclonal, chimeric (or humanized) antibody that targets TNF-alpha. You could maybe try to confirm what kind of a protein it is, ...

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by biohazard
Wed Apr 16, 2008 1:22 pm
 
Forum: General Discussion
Topic: Production of Remicade in Animal Cell Culture
Replies: 5
Views: 724

pharmaceutical biotechnology

... so they don't need NDA, they need BLA, why this drug, gemtuzumab (monoclonal antibody) is NDA but other monoclonal antibodies are BLA? I'll add something below that I take ...

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by kcnq1ot1
Tue Nov 27, 2007 2:47 pm
 
Forum: Molecular Biology
Topic: pharmaceutical biotechnology
Replies: 6
Views: 813

pharmaceutical biotechnology

... here can help me in understanding BLA vs NDA. FDA approved some monoclonal antibody drugs, the list includes gemituzumab, efalizumab, palivizumab, daclizumab etc. Gemituzumab ...

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by kcnq1ot1
Tue Nov 27, 2007 10:29 am
 
Forum: Molecular Biology
Topic: pharmaceutical biotechnology
Replies: 6
Views: 813

The Fiber Disease

... as "guided selection." In this approach a selected non-human monoclonal antibody. The activation of a death-domain receptor. The invention may be associated with heterologous ...

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by Nadas Moksha
Sat Oct 07, 2006 3:47 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 748668
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