Dictionary » M » Mitogen



noun, plural: mitogens

Any substance that triggers mitosis, as well as lymphocyte blastogenesis.


Examples of mitogens are pokeweed mitogen, lipopolysaccharide, phytohaemagglutinin, and concanavalin A.

Word origin: mito(sis) + -gen » Greek -genēs (born, produced).
Related forms: mitogenic (adjective), mitogenicity (noun)

Related terms:

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Proliferation assay

... peaks once the cells start to divide - except that their intensity is high in general. Rather, you might have too much PHA. It is a very powerful mitogen and chances are that it makes all the cells divide -> all cells have undergone equal amounts of cell divisions -> one peak. You could ...

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by biohazard
Wed Jun 13, 2012 7:17 am
Forum: Cell Biology
Topic: Proliferation assay
Replies: 7
Views: 12623

Mitogenesis assay?

Hi, in one of my Labs we conducted a mitogenesis assay on a splenocyte sample using Concanavalin A and Lipopolysacharride as our lectins/mitogens. Different concentrations of mitogen were added to the cell suspension and the plated suspensions ...

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by sam2400
Mon Aug 09, 2010 12:41 pm
Forum: Microbiology
Topic: Mitogenesis assay?
Replies: 2
Views: 4400

help needed - HUVEC-C cells

... targeting using Human Umbilical Endothelial Cell Line - C (HUVEC-C). The growth medium I am is DMEM with 20 % FCS, 0.1 mg/ml heparin, 0.05 mg/ml mitogen (endothelial cell growth supplement) and 1 % Penicillin-streptomycin. The cells grow quite slowly. I am wondering if anyone can give me some ...

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by jmc2
Mon Jan 22, 2007 4:11 pm
Forum: Cell Biology
Topic: help needed - HUVEC-C cells
Replies: 2
Views: 1890

The Fiber Disease

... phone exposure caused a transient increase in phosphorylation of hsp27, an effect which was prevented by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase (p38MAPK). Also, mobile phone exposure caused transient changes in the protein expression levels of hsp27 and p38MAPK. ...

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by London
Fri Dec 01, 2006 11:52 pm
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6246268

Morgellon's or ..........flies, or .......

... referred to as pseudohyphal differentiation. Yeast filamentous growth is regulated, in part, by two conserved signal transduction cascades: a mitogen-activated protein kinase cascade and a G-protein regulated cyclic AMP signaling pathway. Related signaling cascades play an analogous role in ...

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by London
Tue Mar 07, 2006 2:24 am
Forum: Human Biology
Topic: Morgellon's or ..........flies, or .......
Replies: 173
Views: 149463
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