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Referring to mitochondria.

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Re: How did endosymbionts coordinate replication?

Regarding the regulation of replication of mitochondria, this paper discusses an influence of tumor necrosis factor alpha on mitochondrial replication while exploring the effect of adenosine on that regulatory system. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0098459 ...

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by jonmoulton
Wed Jun 11, 2014 2:08 pm
Forum: Cell Biology
Topic: How did endosymbionts coordinate replication?
Replies: 9
Views: 4163

targeting the Aids virus

An antifungal foot cream called Ciclopirox shows abilities to STOP and ERADICATE HIV. It inhibits the expression of it's genes, blocks mitochondrial function and activates the cell suicide pathway. This spares the unaffected healthy cells. HIV couldn't bounce back even after Ciclopirox was ...

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by Sumanth001
Fri Sep 27, 2013 12:40 pm
Forum: General Discussion
Topic: targeting the Aids virus
Replies: 3
Views: 1870

Why must we avert the genome of Eden?

... decades instead of producing only a few when it is necessary. On a GOE based model, the purpose of this feature is to provide uncorrupted, healthy mitochondrial DNA for the offspring. MtDNA mutates magnitudes faster then nDNA (and MtDNA is responsible for ageing), therefore ova are produced early ...

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by Hunor
Mon Sep 23, 2013 12:08 am
Forum: Evolution
Topic: Why must we avert the genome of Eden?
Replies: 6
Views: 7229

Mitochondrial DNA

... thought "the mutational rate of mtDNA is ten fold higher than that of nuclear DNA" and now I read "Although much more slowly, mitochondrial DNA does mutate". Which one is true then? Maybe some references from an expert?

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by kk
Thu Aug 22, 2013 2:25 pm
Forum: Cell Biology
Topic: Mitochondrial DNA
Replies: 17
Views: 8745

Mitochondrial Research

I have not done any mitochondrial studies 1. purify the mitochondria from normal cells check if ETC is going on well by adding succinate 2. divide in to three groups 3. group 1 normal ETC, 2 standard modifier 3 your compound 4. compare ...

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by balamurugan3
Fri Aug 16, 2013 9:52 pm
Forum: General Discussion
Topic: Mitochondrial Research
Replies: 1
Views: 966
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