Dictionary » M » Missense

Missense

Definition

(Of or relating to) A mutation resulting in a codon that codes for a different amino acid, and thus, causes the synthesis of a protein with an altered amino acid sequence during translation.


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protein sequence

Structure determines function but you do not know if structure is altered in a way that inhibits/enhances function. Strictly speaking, benign missense mutation do exist. Of course if your professor told you otherwise, I'd stick with his/her story.

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by mith
Tue Dec 11, 2007 9:09 pm
 
Forum: Molecular Biology
Topic: protein sequence
Replies: 6
Views: 794

synonymous vs conservative missense mutation

... in the resultant protein because the codon encodes the same amino acid e.g. If CAU is changed to CAC it does not matter as both encode histidine. Missense (or non-synonymous) mutations cause base substitution resulting in a codon which encodes a different amino acid e.g. Sickle cell disease is ...

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by Katy_Bobbles
Sat Aug 25, 2007 4:50 pm
 
Forum: Genetics
Topic: synonymous vs conservative missense mutation
Replies: 6
Views: 2263

synonymous vs conservative missense mutation

i don't know the differences between these 2 mutation... look the same to me... and how do we know which mutation will be synonymous/ missense by looking at the change of codon?

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by hiro
Sat Aug 25, 2007 3:07 am
 
Forum: Genetics
Topic: synonymous vs conservative missense mutation
Replies: 6
Views: 2263

Urinary Tract Infection

I copied them down in a lecture I had in November last year. I hadn't noticed the missense of it before. I just thought someone who knows about UTIs might be able to help. My thought is that it means that the change in vaginal pH during pregnancy provides apt conditions ...

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by Katy_Bobbles
Sat Jun 30, 2007 7:29 pm
 
Forum: Microbiology
Topic: Urinary Tract Infection
Replies: 4
Views: 1318

type of mutation

... Point (single-site) mutations in DNA can occur through two possible way, 1-) The substitution of one base pair for another a-)Silent Mutation b-)Missense mutation c-)Non sense mutation 2-)The addition or deletion of a nucleotide pair

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by Seda
Sat Sep 17, 2005 12:28 am
 
Forum: Genetics
Topic: type of mutation
Replies: 4
Views: 2151
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